

| Catalog No. | HS774022 |
|---|---|
| Description |
Recombinant Human FLG2 Protein, N-His-KSI (HS774022) expressed in E. coli, spanning Pro1984-His2391. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q5D862 |
| Protein length | Pro1984-His2391 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 58.60 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | FLG-2, FLG2, Filaggrin-2, IFPS, Ifapsoriasin, Intermediate filament-associated and psoriasis-susceptibility protein |
| Background | Filaggrin-2 is a ~248 kDa protein. Essential for normal cell-cell adhesion in the cornified cell layers. Important for proper integrity and mechanical strength of the stratum corneum of the epidermis. 1. Mohamad, J. et al. (2018) The Journal of investigative dermatology 138, 1736-1743. PMID: 29758285 2. Bolling, MC. et al. (2018) The Journal of investigative dermatology 138, 1881-1884. PMID: 29505760 |
| Note | For research use only |
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