

| Catalog No. | HD819012 |
|---|---|
| Description |
Recombinant Human FYB1 Protein, N-His (HD819012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | O15117 |
| Protein length | Ile510-Ser580&Ala675-Asn766 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | ADAP, Adhesion and degranulation promoting adaptor protein, FYB, FYB-120/130, FYB1, FYN-T-binding protein, FYN-binding protein 1, SLAP-130, SLAP130, SLP-76-associated phosphoprotein, p120/p130 |
| Background | FYN-binding protein 1 is a ~85 kDa protein. Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Modulates the expression of IL2. Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. 1. Krause, M. et al. (2000) The Journal of cell biology 149, 181-94. PMID: 10747096 2. Kliche, S. et al. (2006) Molecular and cellular biology 26, 7130-44. PMID: 16980616 3. Huang, Y. et al. (2005) The Journal of biological chemistry 280, 23576-83. PMID: 15849195 |
| Note | For research use only |
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