Human GLRB Recombinant Protein (N-His) (HD052012)

Name: Human GLRB Recombinant Protein (N-His)
Brand: abinScience
SKU: HD052012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD052012
Description	Recombinant Human GLRB Protein, N-His (HD052012) expressed in E. coli, spanning Ser41-Gln265. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P48167
Protein length	Ser41-Gln265
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	28.40 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	GLRB, Glycine receptor 58 kDa subunit, Glycine receptor subunit beta
Background	Glycine receptor subunit beta is a ~56 kDa protein. Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. 1. Rees, MI. et al. (2002) Human molecular genetics 11, 853-60. PMID: 11929858 2. Miller, PS. et al. (2004) British journal of pharmacology 143, 19-26. PMID: 15302677 3. Miller, PS. et al. (2005) The Journal of biological chemistry 280, 37877-84. PMID: 16144831 4. Yang, Z. et al. (2012) Biochemistry 51, 5229-31. PMID: 22715885 5. James, VM. et al. (2013) Neurobiology of disease 52, 137-49. PMID: 23238346 6. Zhang, Y. et al. (2015) Neuropharmacology 89, 391-7. PMID: 25445488 7. Yu, H. et al. (2021) Neuron 109, 2707-2716.e6. PMID: 34473954 8. Handford, CA. et al. (1996) Brain research. Molecular brain research 35, 211-9. PMID: 8717357
Note	For research use only

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Human GLRB Recombinant Protein (N-His).pdf

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Human GLRB Recombinant Protein (N-His) (HD052012)

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