Human GNA15 Recombinant Protein (N-His) (HC924012)

Name: Human GNA15 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC924012
Price: 211 USD
Availability: InStock

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Catalog No.	HC924012
Description	Recombinant Human GNA15 Protein, N-His (HC924012) expressed in E. coli, spanning Glu42-Leu374. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P30679
Protein length	Glu42-Leu374
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	40.96 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Epididymis tissue protein Li 17E, G alpha-15, G alpha-16, G-protein subunit alpha-15, G-protein subunit alpha-16, GNA15, GNA16, Guanine nucleotide-binding protein subunit alpha-15, Guanine nucleotide-binding protein subunit alpha-16
Background	Guanine nucleotide-binding protein subunit alpha-15 is a ~43 kDa protein. Member of the G-protein alpha subunit family that plays a crucial role in intracellular signaling. Functions as a molecular switch, transducing signals from G protein-coupled receptors (GPCRs) to downstream effectors. In collaboration with the adapter protein TTC1, promotes HRAS activation and ERK1/2 phosphorylation independently of phospholipase Cbeta signaling. Also initiates EMR2-mediated signaling, leading to activation of Akt, MAPK, and NF-kappa-B, which in turn drives macrophage differentiation and inflammatory responses. 1. Marty, C. et al. (2003) Molecular and cellular biology 23, 3847-58. PMID: 12748287 2. Liu, AM. et al. (2010) Cellular signalling 22, 1448-58. PMID: 20639119 3. I, KY. et al. (2017) Frontiers in immunology 8, 373. PMID: 28421075
Note	For research use only

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Datasheet

Human GNA15 Recombinant Protein (N-His).pdf

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Human GNA15 Recombinant Protein (N-His) (HC924012)

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