

| Catalog No. | HC235012 |
|---|---|
| Description |
Recombinant Human GNB1 Protein, N-His (HC235012) expressed in E. coli, spanning Met1-Asn340. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P62873 |
| Protein length | Met1-Asn340 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 39.54 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | GNB1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Transducin beta chain 1 |
| Background | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a ~37 kDa protein. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. 1. García-Nafría, J. et al. (2018) Nature 558, 620-623. PMID: 29925951 2. Xu, P. et al. (2021) Nature 592, 469-473. PMID: 33762731 3. Huang, S. et al. (2021) Cell research 31, 1036-1038. PMID: 34239069 4. Tan, Y. et al. (2022) Cell discovery 8, 50. PMID: 35610220 5. Huang, S. et al. (2022) Molecular cell 82, 2681-2695.e6. PMID: 35714614 6. Zhang, S. et al. (2022) Nature structural & molecular biology 29, 677-687. PMID: 35835867 7. Cao, C. et al. (2022) Neuron 110, 3154-3167.e7. PMID: 36087581 8. He, L. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2209917120. PMID: 36989299 9. Pei, Y. et al. (2023) Biochemical and biophysical research communications 671, 327-334. PMID: 37327704 10. Xu, Z. et al. (2023) Nature 624, 672-681. PMID: 37935376 |
| Note | For research use only |
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