

| Catalog No. | HD185012 |
|---|---|
| Description |
Recombinant Human GRIK3 Protein, N-His (HD185012) expressed in E. coli, spanning Met32-Gly617. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q13003 |
| Protein length | Met32-Gly617 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 68.87 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | EAA5, Excitatory amino acid receptor 5, GLUR7, GRIK3, GluK3, GluR-7, GluR7, Glutamate receptor 7, Glutamate receptor ionotropic, kainate 3 |
| Background | Glutamate receptor ionotropic, kainate 3 is a ~104 kDa protein. Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In association with GRIK2, involved in presynaptic facilitation of glutamate release at hippocampal mossy fiber synapses. 1. Nutt, SL. et al. (1994) Receptors & channels 2, 315-26. PMID: 7719709 |
| Note | For research use only |
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