Human GTF2H1 Recombinant Protein (N-His) (HW750022)

Name: Human GTF2H1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HW750022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HW750022
Description	Recombinant Human GTF2H1 Protein, N-His (HW750022) expressed in E. coli, spanning Met1-Ser156. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P32780
Protein length	Met1-Ser156
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	20.01 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BTF2, BTF2 p62, Basic transcription factor 2 62 kDa subunit, GTF2H1, General transcription factor IIH polypeptide 1, General transcription factor IIH subunit 1, TFIIH basal transcription factor complex p62 subunit
Background	General transcription factor IIH subunit 1 is a ~62 kDa protein. Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
Note	For research use only

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Datasheet

Human GTF2H1 Recombinant Protein (N-His).pdf

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Human GTF2H1 Recombinant Protein (N-His) (HW750022)

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