Human GUCY2D Recombinant Protein (N-His) (HD844012)

Name: Human GUCY2D Recombinant Protein (N-His)
Brand: abinScience
SKU: HD844012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD844012
Description	Recombinant Human GUCY2D Protein, N-His (HD844012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q02846
Protein length	Ala52-Pro453
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CG-E, CORD6, EC:4.6.1.2, GUC1A4, GUC2D, GUCY2D, Guanylate cyclase 2D, retinal, RETGC, RETGC-1, RETGC1, ROS-GC, Retinal guanylyl cyclase 1, Rod outer segment membrane guanylate cyclase
Background	Retinal guanylyl cyclase 1 is a ~120 kDa protein. Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-associated proteins to the photoreceptor outer segment membrane. 1. Tucker, CL. et al. (2004) Molecular vision 10, 297-303. PMID: 15123990 2. Peshenko, IV. et al. (2011) Biochemistry 50, 9511-9. PMID: 21928830 3. Peshenko, IV. et al. (2015) The Journal of biological chemistry 290, 19584-96. PMID: 26100624 4. Wimberg, H. et al. (2018) Frontiers in molecular neuroscience 11, 348. PMID: 30319355 5. Tucker, CL. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 5993-7. PMID: 9600905
Note	For research use only

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Datasheet

Human GUCY2D Recombinant Protein (N-His).pdf

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Human GUCY2D Recombinant Protein (N-His) (HD844012)

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