Human HHEX Recombinant Protein (N-His-KSI) (HD167012)

Name: Human HHEX Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD167012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD167012
Description	Recombinant Human HHEX Protein, N-His-KSI (HD167012) expressed in E. coli, spanning Gln2-Gly270. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q03014
Protein length	Gln2-Gly270
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	45.65 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	HEX, HHEX, Hematopoietically-expressed homeobox protein HHEX, Homeobox protein HEX, Homeobox protein PRH, PRH, PRHX, Proline-rich homeodomain protein
Background	Hematopoietically-expressed homeobox protein HHEX is a ~30 kDa protein. Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. Inhibits EIF4E-mediated mRNA nuclear export. 1. Marfil, V. et al. (2010) The Journal of biological chemistry 285, 5726-37. PMID: 20028982 2. Topisirovic, I. et al. (2003) The EMBO journal 22, 689-703. PMID: 12554669 3. Bedford, FK. et al. (1993) Nucleic acids research 21, 1245-9. PMID: 8096636
Note	For research use only

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Datasheet

Human HHEX Recombinant Protein (N-His-KSI).pdf

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Human HHEX Recombinant Protein (N-His-KSI) (HD167012)

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