Human HIP1 Recombinant Protein (N-His) (HC863012)

Name: Human HIP1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC863012
Price: 211 USD
Availability: InStock

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Catalog No.	HC863012
Description	Recombinant Human HIP1 Protein, N-His (HC863012) expressed in E. coli, spanning Gly23-Ile286. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	O00291
Protein length	Gly23-Ile286
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	32.83 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	HIP-1, HIP-I, HIP1, Huntingtin-interacting protein 1, Huntingtin-interacting protein I
Background	Huntingtin-interacting protein 1 is a ~116 kDa protein. Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Regulates presynaptic nerve terminal activity. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. 1. Waelter, S. et al. (2001) Human molecular genetics 10, 1807-17. PMID: 11532990 2. Mishra, SK. et al. (2001) The Journal of biological chemistry 276, 46230-6. PMID: 11577110 3. Legendre-Guillemin, V. et al. (2002) The Journal of biological chemistry 277, 19897-904. PMID: 11889126 4. Mills, IG. et al. (2005) The Journal of cell biology 170, 191-200. PMID: 16027218 5. Hackam, AS. et al. (2000) The Journal of biological chemistry 275, 41299-308. PMID: 11007801 6. Hyun, TS. et al. (2004) The Journal of biological chemistry 279, 14294-306. PMID: 14732715 7. Wilbur, JD. et al. (2008) The Journal of biological chemistry 283, 32870-9. PMID: 18790740 8. Rao, DS. et al. (2002) The Journal of clinical investigation 110, 351-60. PMID: 12163454
Note	For research use only

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Datasheet

Human HIP1 Recombinant Protein (N-His).pdf

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Human HIP1 Recombinant Protein (N-His) (HC863012)

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