Human HOPX Recombinant Protein (N-His-SUMO & C-Strep) (HC175012)

Name: Human HOPX Recombinant Protein (N-His-SUMO & C-Strep)
Brand: abinScience
SKU: HC175012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC175012
Description	Recombinant Human HOPX Protein, N-His-SUMO & C-Strep (HC175012) expressed in E. coli, spanning Thr10-Leu64. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q9BPY8
Protein length	Thr10-Leu64
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	19.96 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	HOD, HOP, HOPX, Homeodomain-only protein, LAGY, Lung cancer-associated Y protein, NECC1, Not expressed in choriocarcinoma protein 1, OB1, Odd homeobox protein 1
Background	Homeodomain-only protein is a ~8 kDa protein. Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. May act as a tumor suppressor. 1. Seo, JH. et al. (2016) Nature communications 7, 12882. PMID: 27708256
Note	For research use only

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Datasheet

Human HOPX Recombinant Protein (N-His-SUMO & C-Strep).pdf

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Human HOPX Recombinant Protein (N-His-SUMO & C-Strep) (HC175012)

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Datasheet

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