Human HTR4 Recombinant Protein (N-GST & C-His) (HC684032)

Name: Human HTR4 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HC684032
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC684032
Description	Recombinant Human HTR4 Protein, N-GST & C-His (HC684032) expressed in E. coli, spanning Arg214-Thr260. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q13639
Protein length	Arg214-Thr260
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	33.51 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	5-HT-4, 5-HT4, 5-hydroxytryptamine receptor 4, HTR4, Serotonin receptor 4
Background	5-hydroxytryptamine receptor 4 is a ~43 kDa protein. G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. 1. Mialet, J. et al. (2000) British journal of pharmacology 130, 527-38. PMID: 10821780 2. Kamel, R. et al. (2005) Biochemical pharmacology 70, 1009-18. PMID: 16102731 3. Huang, S. et al. (2022) Molecular cell 82, 2681-2695.e6. PMID: 35714614 4. Blondel, O. et al. (1998) Journal of neurochemistry 70, 2252-61. PMID: 9603189
Note	For research use only

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Datasheet

Human HTR4 Recombinant Protein (N-GST & C-His).pdf

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Human HTR4 Recombinant Protein (N-GST & C-His) (HC684032)

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