

| Catalog No. | HD788012 |
|---|---|
| Description |
Recombinant Human IBSP Protein, N-His-KSI (HD788012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | P21815 |
| Protein length | Phe17-Gln317 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | BNSP, BSP II, Bone sialoprotein 2, Bone sialoprotein II, Cell-binding sialoprotein, IBSP, Integrin-binding sialoprotein |
| Background | Integrin-binding sialoprotein is a ~35 kDa protein. Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes adhesion and migration of various cells via the alpha-V/beta-3 integrin receptor (ITGAV:ITGB3). 1. Wuttke, M. et al. (2001) The Journal of biological chemistry 276, 36839-48. PMID: 11459848 2. Bianco, P. et al. (1991) Calcified tissue international 49, 421-6. PMID: 1818768 3. Byzova, TV. et al. (2000) Experimental cell research 254, 299-308. PMID: 10640428 4. Rapuano, BE. et al. (2013) European journal of oral sciences 121, 600-9. PMID: 24103036 |
| Note | For research use only |
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