Human IER5 Recombinant Protein (N-His-KSI) (HD306012)

Name: Human IER5 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD306012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD306012
Description	Recombinant Human IER5 Protein, N-His-KSI (HD306012) expressed in E. coli, spanning Glu2-Pro166. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q5VY09
Protein length	Glu2-Pro166
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	32.95 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IER5, Immediate early response gene 5 protein
Background	Immediate early response gene 5 protein is a ~33 kDa protein. Plays a role as a transcription factor. Mediates positive transcriptional regulation of several chaperone genes during the heat shock response in a HSF1-dependent manner. Mediates negative transcriptional regulation of CDC25B expression. Plays a role in the dephosphorylation of the heat shock factor HSF1 and ribosomal protein S6 kinase (S6K) by the protein phosphatase PP2A. Involved in the regulation of cell proliferation and resistance to thermal stress. 1. Nakamura, S. et al. (2011) PloS one 6, e28011. PMID: 22132193 2. Ishikawa, Y. et al. (2015) The FEBS journal 282, 332-40. PMID: 25355627 3. Ishikawa, Y. et al. (2015) FEBS letters 589, 1150-5. PMID: 25816751 4. Kawabata, S. et al. (2015) FEBS letters 589, 3679-85. PMID: 26496226
Note	For research use only

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Datasheet

Human IER5 Recombinant Protein (N-His-KSI).pdf

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Human IER5 Recombinant Protein (N-His-KSI) (HD306012)

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