Human IgM Recombinant Protein (HV496011)

Name: Human IgM Recombinant Protein
Brand: abinScience
SKU: HV496011
Price: 298 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.	HV496011
Description	Recombinant Human IgM Protein (HV496011) expressed in Mammalian Cells. Purity: >90% by SDS-PAGE. Highlights ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Accession	P01871
Protein length	Full length.
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Clonality	Monoclonal
Species	Homo sapiens (Human)
Nature	Recombinant
Target	IGHM, Ig mu chain C region, Ig mu chain C region BOT, Ig mu chain C region GAL, Ig mu chain C region OU, Immunoglobulin heavy constant mu
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IgM, Immunoglobulin mu
Background	Immunoglobulin heavy constant mu (lgM) is a ~51 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. 1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268 2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414 3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Recombinant Human IgM Protein
Bioactivity

Detected by SAA1253 (Catalog No: HV496013) in indirect ELISA.
Bioactivity

Detected by SAA2369 (Catalog No: HV496023) in indirect ELISA.

References

Datasheet

Human IgM Recombinant Protein.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

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Recombinant Proteins

Antibodies

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Human IgM Recombinant Protein (HV496011)

Overview

Images

References

Datasheet

SDS