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Human IL1RAPL1 Recombinant Protein (C-Fc) (HD150021)

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Overview
Catalog No.HD150021
Description
Recombinant Human IL1RAPL1 Protein, C-Fc (HD150021) expressed in Mammalian Cells, spanning Leu19-Leu354. Purity: >90% by SDS-PAGE.
Highlights
  • Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • Mammalian Expression — Proper folding and native glycosylation.
  • High Purity — >90% purity verified by SDS-PAGE.
Expression systemMammalian cells
AccessionQ9NZN1
Protein lengthLeu19-Leu354
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Predicted molecular weight 66.85 kDa
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesEC:3.2.2.6, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, IL1RAPL1, Interleukin-1 receptor accessory protein-like 1, OPHN4, Oligophrenin-4, TIGIRR-2, Three immunoglobulin domain-containing IL-1 receptor-related 2, X-linked interleukin-1 receptor accessory protein-like 1
Background

Interleukin-1 receptor accessory protein-like 1 is a ~79 kDa protein. May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.

1. Bahi, N. et al. (2003) Human molecular genetics 12, 1415-25. PMID: 12783849
2. Khan, JA. et al. (2004) The Journal of biological chemistry 279, 31664-70. PMID: 15123616
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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