Human INO80 Recombinant Protein (N-His) (HD926012)

Name: Human INO80 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD926012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD926012
Description	Recombinant Human INO80 Protein, N-His (HD926012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q9ULG1
Protein length	Gly520-Glu752
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Chromatin-remodeling ATPase INO80, DNA helicase-related INO80 complex homolog 1, DNA helicase-related protein INO80, EC:3.6.4.-, INO80, INO80 complex subunit A, INO80A, INOC1, KIAA1259, hINO80
Background	Chromatin-remodeling ATPase INO80 is a ~176 kDa protein. ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair. Binds DNA. As part of the INO80 complex, remodels chromatin by shifting nucleosomes. Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator. Involved in UV-damage excision DNA repair. 1. Jin, J. et al. (2005) The Journal of biological chemistry 280, 41207-12. PMID: 16230350 2. Bakshi, R. et al. (2006) Biochemical and biophysical research communications 339, 313-20. PMID: 16298340 3. Cai, Y. et al. (2007) Nature structural & molecular biology 14, 872-4. PMID: 17721549 4. Hur, SK. et al. (2010) Cellular and molecular life sciences : CMLS 67, 2283-96. PMID: 20237820 5. Jiang, Y. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 17274-9. PMID: 20855601 6. Chen, L. et al. (2011) The Journal of biological chemistry 286, 11283-9. PMID: 21303910
Note	For research use only

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Datasheet

Human INO80 Recombinant Protein (N-His).pdf

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Human INO80 Recombinant Protein (N-His) (HD926012)

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