Human IRF2 Recombinant Protein (N-His) (HD001012)

Name: Human IRF2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD001012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD001012
Description	Recombinant Human IRF2 Protein, N-His (HD001012) expressed in E. coli, spanning Met1-Pro113. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P14316
Protein length	Met1-Pro113
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	15.58 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	IRF-2, IRF2, Interferon regulatory factor 2
Background	Interferon regulatory factor 2 is a ~39 kDa protein. DNA-binding transcription factor that specifically binds to the upstream regulatory region of type I interferon (IFN) and IFN-inducible genes and regulates their expression. Mainly acts as a transcription repressor, repressing expression. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. 1. Danac, JMC. et al. (2024) Molecular cell 84, 2870-2881.e5. PMID: 39013473 2. Tanaka, N. et al. (1993) Molecular and cellular biology 13, 4531-8. PMID: 7687740 3. Oshima, S. et al. (2004) Molecular and cellular biology 24, 6298-310. PMID: 15226432 4. Aziz, F. et al. (1998) Molecular biology reports 25, 1-12. PMID: 9540062
Note	For research use only

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Datasheet

Human IRF2 Recombinant Protein (N-His).pdf

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Human IRF2 Recombinant Protein (N-His) (HD001012)

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