Human ISG20 Recombinant Protein (N-His) (HD995012)

Name: Human ISG20 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD995012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD995012
Description	Recombinant Human ISG20 Protein, N-His (HD995012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q96AZ6
Protein length	Met1-Asp181
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EC:3.1.13.1, Estrogen-regulated transcript 45 protein, HEM45, ISG20, Interferon-stimulated gene 20 kDa protein, Promyelocytic leukemia nuclear body-associated protein ISG20
Background	Interferon-stimulated gene 20 kDa protein is a ~20 kDa protein. Interferon-induced antiviral exoribonuclease that acts mainly on single-stranded RNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV). Inhibition of several viruses such as chikungunya virus (CHIKV) does not involve the degradation of viral RNAs, but rather the inhibition of translation of viral proteins. Exerts a translational control over a large panel of non-self RNA substrates while sparing endogenous transcripts. This activity correlates with the protein's ability to localize in cytoplasmic processing bodies. 1. Nguyen, LH. et al. (2001) Biochemistry 40, 7174-9. PMID: 11401564 2. Espert, L. et al. (2003) The Journal of biological chemistry 278, 16151-8. PMID: 12594219 3. Espert, L. et al. (2005) The Journal of general virology 86, 2221-2229. PMID: 16033969 4. Espert, L. et al. (2006) Journal of cellular biochemistry 98, 1320-33. PMID: 16514659 5. Zhou, Z. et al. (2011) Virology 409, 175-88. PMID: 21036379 6. Wu, N. et al. (2019) PLoS pathogens 15, e1008093. PMID: 31600344
Note	For research use only

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Datasheet

Human ISG20 Recombinant Protein (N-His).pdf

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Human ISG20 Recombinant Protein (N-His) (HD995012)

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