Human KCNC1 Recombinant Protein (N-His) (HW529012)

Name: Human KCNC1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HW529012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HW529012
Description	Recombinant Human KCNC1 Protein, N-His (HW529012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P48547
Protein length	Met1-Arg190
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	KCNC1, NGK2, Potassium voltage-gated channel subfamily C member 1, Voltage-gated potassium channel KCNC1, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4
Background	Voltage-gated potassium channel KCNC1 is a ~57 kDa protein. Voltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient. The mechanism is time-dependent and inactivation is slow. Plays an important role in the rapid repolarization of fast-firing brain neurons. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons. 1. Muona, M. et al. (2015) Nature genetics 47, 39-46. PMID: 25401298 2. Chi, G. et al. (2022) Nature communications 13, 4087. PMID: 35840580
Note	For research use only

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Datasheet

Human KCNC1 Recombinant Protein (N-His).pdf

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Human KCNC1 Recombinant Protein (N-His) (HW529012)

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