Human MAFA Recombinant Protein (N-His) (HD984012)

Name: Human MAFA Recombinant Protein (N-His)
Brand: abinScience
SKU: HD984012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD984012
Description	Recombinant Human MAFA Protein, N-His (HD984012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q8NHW3
Protein length	Arg226-Ala318
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	MAFA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, Transcription factor MafA, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
Background	Transcription factor MafA is a ~36 kDa protein. Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence. 1. Olbrot, M. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 6737-42. PMID: 12011435 2. Aramata, S. et al. (2005) Biochimica et biophysica acta 1730, 41-6. PMID: 15993959 3. Lu, X. et al. (2012) Biochemistry 51, 9706-17. PMID: 23148532 4. Iacovazzo, D. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 1027-1032. PMID: 29339498
Note	For research use only

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Datasheet

Human MAFA Recombinant Protein (N-His).pdf

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Human MAFA Recombinant Protein (N-His) (HD984012)

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