

| Catalog No. | HA178022 |
|---|---|
| Description |
Recombinant Human MALSU1 Protein, N-His (HA178022) expressed in E. coli, spanning Lys91-Glu234. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q96EH3 |
| Protein length | Lys91-Glu234 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 19.12 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | C7orf30, MALSU1, Mitochondrial assembly of ribosomal large subunit protein 1 |
| Background | Mitochondrial assembly of ribosomal large subunit protein 1 is a ~26 kDa protein. Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein uL14m (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome. 1. Wanschers, BF. et al. (2012) Nucleic acids research 40, 4040-51. PMID: 22238375 2. Fung, S. et al. (2013) Molecular biology of the cell 24, 184-93. PMID: 23171548 3. Rorbach, J. et al. (2012) Nucleic acids research 40, 4097-109. PMID: 22238376 |
| Note | For research use only |
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