Human MAP2K5 Recombinant Protein (N-His) (HD193012)

Name: Human MAP2K5 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD193012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD193012
Description	Recombinant Human MAP2K5 Protein, N-His (HD193012) expressed in E. coli, spanning Ser144-Pro448. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q13163
Protein length	Ser144-Pro448
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	36.54 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Dual specificity mitogen-activated protein kinase kinase 5, EC:2.7.12.2, MAP kinase kinase 5, MAP2K5, MAPK/ERK kinase 5, MAPKK 5, MEK 5, MEK5, MKK5, PRKMK5
Background	Dual specificity mitogen-activated protein kinase kinase 5 is a ~50 kDa protein. Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis. As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via promotion of STUB1/CHIP-mediated ubiquitination and degradation of ICER-type isoforms of CREM.
Note	For research use only

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Datasheet

Human MAP2K5 Recombinant Protein (N-His).pdf

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Human MAP2K5 Recombinant Protein (N-His) (HD193012)

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