

| Catalog No. | HC957012 |
|---|---|
| Description |
Recombinant Human MED24 Protein, N-His (HC957012) expressed in E. coli, spanning Thr278-Thr690. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | O75448 |
| Protein length | Thr278-Thr690 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 48.35 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | ARC100, Activator-recruited cofactor 100 kDa component, CRSP complex subunit 4, CRSP4, Cofactor required for Sp1 transcriptional activation subunit 4, DRIP100, KIAA0130, MED24, Mediator complex subunit 24, Mediator of RNA polymerase II transcription subunit 24, THRAP4, TRAP100, Thyroid hormone receptor-associated protein 4, Thyroid hormone receptor-associated protein complex 100 kDa component, Trap100, Vitamin D3 receptor-interacting protein complex 100 kDa component, hTRAP100 |
| Background | Mediator of RNA polymerase II transcription subunit 24 is a ~110 kDa protein. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
| Note | For research use only |
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