

| Catalog No. | HP179022 |
|---|---|
| Description |
Recombinant Human MICOS13 Protein, N-GST & C-His (HP179022) expressed in E. coli, spanning Asp27-Lys118. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q5XKP0 |
| Protein length | Asp27-Lys118 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 38.40 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | C19orf70, MIC13, MICOS complex subunit MIC13, MICOS13, Protein P117, QIL1 |
| Background | MICOS complex subunit MIC13 is a ~13 kDa protein. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology. Required for the incorporation of MICOS10/MIC10 into the MICOS complex. 1. Guarani, V. et al. (2015) eLife 4. PMID: 25997101 2. Guarani, V. et al. (2016) eLife 5. PMID: 27623147 3. Stephan, T. et al. (2020) The EMBO journal 39, e104105. PMID: 32567732 |
| Note | For research use only |
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