Human MLLT1 Recombinant Protein (N-His) (HD847012)

Name: Human MLLT1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD847012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD847012
Description	Recombinant Human MLLT1 Protein, N-His (HD847012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q03111
Protein length	Met1-Pro145
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ENL, Eleven-nineteen-leukeumia, LTG19, MLLT1, Protein ENL, YEATS domain-containing protein 1, YEATS1
Background	Protein ENL is a ~62 kDa protein. Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acetylated and crotonylated histones, with a preference for histones that are crotonylated. Has a slightly higher affinity for binding histone H3 crotonylated at 'Lys-27' (H3K27cr) than 'Lys-20' (H3K9cr20). May play a role in leukemogenic gene transcription. 1. Lin, C. et al. (2010) Molecular cell 37, 429-37. PMID: 20159561 2. He, N. et al. (2010) Molecular cell 38, 428-38. PMID: 20471948 3. Li, Y. et al. (2016) Molecular cell 62, 181-193. PMID: 27105114 4. Becht, DC. et al. (2025) Nature structural & molecular biology 32, 709-718. PMID: 39794553
Note	For research use only

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Datasheet

Human MLLT1 Recombinant Protein (N-His).pdf

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Human MLLT1 Recombinant Protein (N-His) (HD847012)

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