

| Catalog No. | HD811012 |
|---|---|
| Description |
Recombinant Human MPC2 Protein, N-GST & C-His (HD811012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | O95563 |
| Protein length | Ser2-Val41&Arg62-Ser72&Arg116-Lys127 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | BRP44, Brain protein 44, MPC2, Mitochondrial pyruvate carrier 2 |
| Background | Mitochondrial pyruvate carrier 2 is a ~14 kDa protein. Mediates the uptake of pyruvate into mitochondria to maintain the balance between glycolysis and oxidative phosphorylation. Plays an essential role in cellular metabolism. 1. Bricker, DK. et al. (2012) Science (New York, N.Y.) 337, 96-100. PMID: 22628558 2. Compan, V. et al. (2015) Molecular cell 59, 491-501. PMID: 26253029 3. Vanderperre, B. et al. (2016) The Journal of biological chemistry 291, 16448-61. PMID: 27317664 4. Nagampalli, RSK. et al. (2018) Scientific reports 8, 3510. PMID: 29472561 5. He, Z. et al. (2025) Nature 641, 250-257. PMID: 40044865 6. Liang, J. et al. (2025) Nature 641, 258-265. PMID: 40101766 7. Tavoulari, S. et al. (2022) Molecular metabolism 60, 101469. PMID: 35278701 |
| Note | For research use only |
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