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Human MPC2 Recombinant Protein (N-GST & C-His) (HD811012)

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Overview
Catalog No.HD811012
Description
Recombinant Human MPC2 Protein, N-GST & C-His (HD811012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% as determined by SDS-PAGE.
Expression systemE. coli
AccessionO95563
Protein lengthSer2-Val41&Arg62-Ser72&Arg116-Lys127
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBRP44, Brain protein 44, MPC2, Mitochondrial pyruvate carrier 2
Background

Mitochondrial pyruvate carrier 2 is a ~14 kDa protein. Mediates the uptake of pyruvate into mitochondria to maintain the balance between glycolysis and oxidative phosphorylation. Plays an essential role in cellular metabolism.

1. Bricker, DK. et al. (2012) Science (New York, N.Y.) 337, 96-100. PMID: 22628558
2. Compan, V. et al. (2015) Molecular cell 59, 491-501. PMID: 26253029
3. Vanderperre, B. et al. (2016) The Journal of biological chemistry 291, 16448-61. PMID: 27317664
4. Nagampalli, RSK. et al. (2018) Scientific reports 8, 3510. PMID: 29472561
5. He, Z. et al. (2025) Nature 641, 250-257. PMID: 40044865
6. Liang, J. et al. (2025) Nature 641, 258-265. PMID: 40101766
7. Tavoulari, S. et al. (2022) Molecular metabolism 60, 101469. PMID: 35278701
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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