Human MRPL12 Recombinant Protein (N-GST & C-His) (HC170012)

Name: Human MRPL12 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HC170012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC170012
Description	Recombinant Human MRPL12 Protein, N-GST & C-His (HC170012) expressed in E. coli, spanning His129-Glu198. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P52815
Protein length	His129-Glu198
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	35.85 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	39S ribosomal protein L12, mitochondrial, 5c5-2, L12mt, Large ribosomal subunit protein bL12m, Large ribosomal subunit protein bL12m, long mature form, Large ribosomal subunit protein bL12m, short mature form, MRP-L12, MRPL12, MRPL7, RPML12
Background	Large ribosomal subunit protein bL12m is a ~21 kDa protein. As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation. When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription. Required for POLRMT stability. 1. Serre, V. et al. (2013) Biochimica et biophysica acta 1832, 1304-12. PMID: 23603806 2. Surovtseva, YV. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 17921-6. PMID: 22003127 3. Nouws, J. et al. (2016) The Journal of biological chemistry 291, 989-97. PMID: 26586915
Note	For research use only

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Datasheet

Human MRPL12 Recombinant Protein (N-GST & C-His).pdf

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Human MRPL12 Recombinant Protein (N-GST & C-His) (HC170012)

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