

| Catalog No. | HC989012 |
|---|---|
| Description |
Recombinant Human MYBL1 Protein, N-His (HC989012) expressed in E. coli, spanning Gly28-Asp196. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | P10243 |
| Protein length | Gly28-Asp196 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 22.74 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | A-Myb, AMYB, MYBL1, Myb-like protein 1, Myb-related protein A |
| Background | Myb-related protein A is a ~85 kDa protein. Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Transcriptional activator of SOX30. 1. Ma, XP. et al. (1994) Cancer research 54, 6512-6. PMID: 7987850 2. Golay, J. et al. (1994) Oncogene 9, 2469-79. PMID: 8058310 |
| Note | For research use only |
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