Human NLRC4 Recombinant Protein (N-His) (HC156012)

Name: Human NLRC4 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC156012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC156012
Description	Recombinant Human NLRC4 Protein, N-His (HC156012) expressed in E. coli, spanning Asn764-Phe1019. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q9NPP4
Protein length	Asn764-Phe1019
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	31.16 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CARD, LRR, and NACHT-containing protein, CARD12, CED-4-like protein Clan, CLAN, CLAN1, Caspase recruitment domain-containing protein 12, IPAF, Ice protease-activating factor, Ipaf, NLR family CARD domain-containing protein 4, NLRC4
Background	NLR family CARD domain-containing protein 4 is a ~116 kDa protein. Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis. The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria. 1. Damiano, JS. et al. (2004) The Biochemical journal 381, 213-9. PMID: 15107016
Note	For research use only

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Datasheet

Human NLRC4 Recombinant Protein (N-His).pdf

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Human NLRC4 Recombinant Protein (N-His) (HC156012)

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