Human NR4A1 Recombinant Protein (N-His) (HD945012)

Name: Human NR4A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD945012
Price: 211 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HD945012
Description	Recombinant Human NR4A1 Protein, N-His (HD945012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P22736
Protein length	Lys397-Phe598
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Early response protein NAK1, GFRP1, HMR, NAK1, NR4A1, Nuclear hormone receptor NUR/77, Nuclear receptor subfamily 4immunitygroup A member 1, Nur77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3
Background	Nuclear receptor subfamily 4immunitygroup A member 1 is a ~64 kDa protein. Orphan nuclear receptor. Binds the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Binds 9-cis-retinoic acid outside of its ligand-binding (NR LBD) domain. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Regulates the inflammatory response in macrophages by regulating metabolic adaptations during inflammation, including repressing the transcription of genes involved in the citric acid cycle (TCA). 1. Zhan, Y. et al. (2008) Nature chemical biology 4, 548-56. PMID: 18690216 2. Woronicz, JD. et al. (1994) Nature 367, 277-81. PMID: 8121493 3. Philips, A. et al. (1997) Molecular and cellular biology 17, 5946-51. PMID: 9315652 4. Zhan, YY. et al. (2012) Nature chemical biology 8, 897-904. PMID: 22983157 5. Harant, H. et al. (2004) Nucleic acids research 32, 5280-90. PMID: 15466594
Note	For research use only

Images

References

Datasheet

Human NR4A1 Recombinant Protein (N-His).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Human NR4A1 Recombinant Protein (N-His) (HD945012)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us