

| Catalog No. | HP367022 |
|---|---|
| Description |
Recombinant Human OSGIN1 Protein, N-His (HP367022) expressed in E. coli, spanning Leu269-Val394. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q9UJX0 |
| Protein length | Leu269-Val394 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 16.26 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | BDGI, BMSC-derived growth inhibitor, Bone marrow stromal cell-derived growth inhibitor, EC:1.14.13.-, OKL38, OSGIN1, Ovary, kidney and liver protein 38, Oxidative stress-induced growth inhibitor 1, Pregnancy-induced growth inhibitor OKL38, huOKL38 |
| Background | Oxidative stress-induced growth inhibitor 1 is a ~51 kDa protein. Monooxygenase catalytic activity. Involved in regulation of cytokinesis; promotes RHOA activity, probably acting locally at the midbody in late cytokinesis. Monooxygenase activity is involved in stabilizing transient structures between daughter cells, termed intercellular bridges, before abscission. Regulates differentiation and proliferation through the regulation of cell death. 1. Goupil, E. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2308570121. PMID: 38442170 2. Huynh, H. et al. (2001) Endocrinology 142, 3607-15. PMID: 11459809 3. Ong, CK. et al. (2004) The Journal of biological chemistry 279, 743-54. PMID: 14570898 |
| Note | For research use only |
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