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Human OSGIN1 Recombinant Protein (N-His) (HP367022)

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Overview
Catalog No.HP367022
Description
Recombinant Human OSGIN1 Protein, N-His (HP367022) expressed in E. coli, spanning Leu269-Val394. Purity: >90% by SDS-PAGE.
Highlights
  • His-Tagged — N-terminal 6×His tag for IMAC purification.
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% purity verified by SDS-PAGE.
Expression systemE. coli
AccessionQ9UJX0
Protein lengthLeu269-Val394
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Predicted molecular weight 16.26 kDa
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBDGI, BMSC-derived growth inhibitor, Bone marrow stromal cell-derived growth inhibitor, EC:1.14.13.-, OKL38, OSGIN1, Ovary, kidney and liver protein 38, Oxidative stress-induced growth inhibitor 1, Pregnancy-induced growth inhibitor OKL38, huOKL38
Background

Oxidative stress-induced growth inhibitor 1 is a ~51 kDa protein. Monooxygenase catalytic activity. Involved in regulation of cytokinesis; promotes RHOA activity, probably acting locally at the midbody in late cytokinesis. Monooxygenase activity is involved in stabilizing transient structures between daughter cells, termed intercellular bridges, before abscission. Regulates differentiation and proliferation through the regulation of cell death.

1. Goupil, E. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2308570121. PMID: 38442170
2. Huynh, H. et al. (2001) Endocrinology 142, 3607-15. PMID: 11459809
3. Ong, CK. et al. (2004) The Journal of biological chemistry 279, 743-54. PMID: 14570898
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Volume
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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