Human PKD1 Recombinant Protein (N-His) (HD834012)

Name: Human PKD1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD834012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD834012
Description	Recombinant Human PKD1 Protein, N-His (HD834012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P98161
Protein length	Leu3686-Leu3902
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Autosomal dominant polycystic kidney disease 1 protein, PC1, PKD1, Polycystin-1
Background	Polycystin-1 is a ~462 kDa protein. Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Both PKD1 and PKD2 are required for channel activity. Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. 1. Kim, S. et al. (2016) Nature cell biology 18, 752-764. PMID: 27214281 2. Qian, F. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 16981-6. PMID: 12482949 3. Lea, WA. et al. (2023) Cells 12. PMID: 37681898
Note	For research use only

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Datasheet

Human PKD1 Recombinant Protein (N-His).pdf

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Human PKD1 Recombinant Protein (N-His) (HD834012)

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