

| Catalog No. | HC881012 |
|---|---|
| Description |
Recombinant Human PRORP Protein, N-His (HC881012) expressed in E. coli, spanning Asn120-Thr583. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | O15091 |
| Protein length | Asn120-Thr583 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 56.12 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | EC:3.1.26.5, KIAA0391, MRPP3, Mitochondrial RNase P protein 3, Mitochondrial ribonuclease P catalytic subunit, Mitochondrial ribonuclease P protein 3, PRORP, Protein only RNase P catalytic subunit |
| Background | Mitochondrial ribonuclease P catalytic subunit is a ~67 kDa protein. Catalytic ribonuclease component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. The presence of TRMT10C/MRPP1, HSD17B10/MRPP2 is required to catalyze tRNA molecules in their 5'-ends. 1. Holzmann, J. et al. (2008) Cell 135, 462-74. PMID: 18984158 2. Reinhard, L. et al. (2015) Nucleic acids research 43, 5664-72. PMID: 25953853 3. Hochberg, I. et al. (2021) American journal of human genetics 108, 2195-2204. PMID: 34715011 |
| Note | For research use only |
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