Human RAB21 Recombinant Protein (N-His) (HV977022)

Name: Human RAB21 Recombinant Protein (N-His)
Brand: abinScience
SKU: HV977022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HV977022
Description	Recombinant Human RAB21 Protein, N-His (HV977022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q9UL25
Protein length	Ala17-Gly194
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EC:3.6.5.2, KIAA0118, RAB21, Ras-related protein Rab-21
Background	Ras-related protein Rab-21 is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB21 is involved in membrane trafficking control. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. 1. Pellinen, T. et al. (2008) Developmental cell 15, 371-385. PMID: 18804435 2. Jean, S. et al. (2015) EMBO reports 16, 297-311. PMID: 25648148 3. Del Olmo, T. et al. (2019) Biology open 8. PMID: 31455601
Note	For research use only

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Datasheet

Human RAB21 Recombinant Protein (N-His).pdf

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Human RAB21 Recombinant Protein (N-His) (HV977022)

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