Human RANBP1 Recombinant Protein (N-His) (HD034012)

Name: Human RANBP1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD034012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD034012
Description	Recombinant Human RANBP1 Protein, N-His (HD034012) expressed in E. coli, spanning Asp44-Gln201. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P43487
Protein length	Asp44-Gln201
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	20.74 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	RANBP1, Ran-binding protein 1, Ran-specific GTPase-activating protein, RanBP1
Background	Ran-specific GTPase-activating protein is a ~23 kDa protein. Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus. Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins. Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L. 1. Koyama, M. et al. (2010) The EMBO journal 29, 2002-13. PMID: 20485264 2. Li, HY. et al. (2007) Cell cycle (Georgetown, Tex.) 6, 1886-95. PMID: 17671426 3. Bischoff, FR. et al. (1995) The EMBO journal 14, 705-15. PMID: 7882974 4. Hayashi, N. et al. (1995) Molecular & general genetics : MGG 247, 661-9. PMID: 7616957
Note	For research use only

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Human RANBP1 Recombinant Protein (N-His).pdf

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Human RANBP1 Recombinant Protein (N-His) (HD034012)

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