Human RBL1 Recombinant Protein (N-His) (HD937012)

Name: Human RBL1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD937012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD937012
Description	Recombinant Human RBL1 Protein, N-His (HD937012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P28749
Protein length	Thr391-Ser581
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	107 kDa retinoblastoma-associated protein, RBL1, Retinoblastoma-like protein 1, p107, pRb1
Background	Retinoblastoma-like protein 1 is a ~120 kDa protein. Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. 1. Schmit, F. et al. (2007) Cell cycle (Georgetown, Tex.) 6, 1903-13. PMID: 17671431 2. Zhu, L. et al. (1993) Genes & development 7, 1111-25. PMID: 8319904
Note	For research use only

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Datasheet

Human RBL1 Recombinant Protein (N-His).pdf

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Human RBL1 Recombinant Protein (N-His) (HD937012)

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