Human RBM47 Recombinant Protein (N-His) (HC868012)

Name: Human RBM47 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC868012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC868012
Description	Recombinant Human RBM47 Protein, N-His (HC868012) expressed in E. coli, spanning Asn31-Gly334. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	A0AV96
Protein length	Asn31-Gly334
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	36.94 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	RBM47, RNA-binding motif protein 47, RNA-binding protein 47
Background	RNA-binding protein 47 is a ~64 kDa protein. Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing. Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1. With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules. Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10. Also involved in the alternative splicing of several genes including TJP1. 1. Guan, R. et al. (2013) Developmental dynamics : an official publication of the American Association of Anatomists 242, 1395-404. PMID: 24038582 2. Fossat, N. et al. (2014) EMBO reports 15, 903-10. PMID: 24916387 3. Cieply, B. et al. (2016) Cell reports 15, 247-55. PMID: 27050523 4. Wolfe, AD. et al. (2019) Journal of molecular biology 431, 1506-1517. PMID: 30844405 5. Kim, YE. et al. (2019) Oncogene 38, 6521-6536. PMID: 31358901 6. Wang, K. et al. (2021) EMBO reports 22, e52205. PMID: 34160127
Note	For research use only

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Datasheet

Human RBM47 Recombinant Protein (N-His).pdf

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Human RBM47 Recombinant Protein (N-His) (HC868012)

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