

| Catalog No. | HC893012 |
|---|---|
| Description |
Recombinant Human RGS16 Protein, N-His (HC893012) expressed in E. coli, spanning Met1-Thr202. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | O15492 |
| Protein length | Met1-Thr202 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 24.91 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | A28-RGS14P, RGS-r, RGS16, RGSR, Regulator of G-protein signaling 16, Retinal-specific RGS, Retinally abundant regulator of G-protein signaling, hRGS-r |
| Background | Regulator of G-protein signaling 16 is a ~22 kDa protein. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals. 1. Derrien, A. et al. (2001) The Journal of biological chemistry 276, 48532-8. PMID: 11602604 2. Soundararajan, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6457-62. PMID: 18434541 |
| Note | For research use only |
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