Human RNASE6 Recombinant Protein (C-His) (HD339011)

Name: Human RNASE6 Recombinant Protein (C-His)
Brand: abinScience
SKU: HD339011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	HD339011
Description	Recombinant Human RNASE6 Protein, C-His (HD339011) expressed in Yeast Cells, spanning Trp24-Leu150. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Yeast cells
Accession	Q93091
Protein length	Trp24-Leu150
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	15.97 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EC:3.1.27.-, RNASE6, RNS6, RNase K6, Ribonuclease K6
Background	Ribonuclease K6 is a ~17 kDa protein. Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli. Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. 1. Prats-Ejarque, G. et al. (2016) The Biochemical journal 473, 1523-36. PMID: 27013146 2. Rosenberg, HF. et al. (1996) Nucleic acids research 24, 3507-13. PMID: 8836175 3. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772 4. Pulido, D. et al. (2016) International journal of molecular sciences 17, 552. PMID: 27089320
Note	For research use only

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Datasheet

Human RNASE6 Recombinant Protein (C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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Human RNASE6 Recombinant Protein (C-His) (HD339011)

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