

| Catalog No. | HC738012 |
|---|---|
| Description |
Recombinant Human SART3 Protein, N-His (HC738012) expressed in E. coli, spanning Asp111-Ser558. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q15020 |
| Protein length | Asp111-Ser558 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 55.08 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | KIAA0156, SART-3, SART3, Spliceosome associated factor 3, U4/U6 recycling protein, Squamous cell carcinoma antigen recognized by T-cells 3, TIP110, Tat-interacting protein of 110 kDa, Tip110, p110 nuclear RNA-binding protein |
| Background | Spliceosome associated factor 3, U4/U6 recycling protein is a ~109 kDa protein. U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites. May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. 1. Bell, M. et al. (2002) The EMBO journal 21, 2724-35. PMID: 12032085 2. Damianov, A. et al. (2004) Molecular and cellular biology 24, 1700-8. PMID: 14749385 3. Song, EJ. et al. (2010) Genes & development 24, 1434-47. PMID: 20595234 4. Long, L. et al. (2014) The Journal of biological chemistry 289, 8916-30. PMID: 24526689 |
| Note | For research use only |
Contact us for custom quotes, bulk requests and any other issues.
Mail: [email protected]
+86-27-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский