Human SCNN1G Recombinant Protein (N-His) (HD983012)

Name: Human SCNN1G Recombinant Protein (N-His)
Brand: abinScience
SKU: HD983012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD983012
Description	Recombinant Human SCNN1G Protein, N-His (HD983012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P51170
Protein length	Thr80-Asn522
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Amiloride-sensitive sodium channel subunit gamma, ENaC subunit gamma, ENaCG, Epithelial Na(+) channel subunit gamma, Epithelial sodium channel subunit gamma, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG, SCNN1G, Sodium channel epithelial 1 subunit gamma
Background	Epithelial sodium channel subunit gamma is a ~74 kDa protein. This is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis. ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. Additionally, ENaC is essential for airway surface liquid homeostasis, which is crucial for proper mucus clearance. 1. Noreng, S. et al. (2018) eLife 7. PMID: 30251954 2. Noreng, S. et al. (2020) eLife 9. PMID: 32729833 3. Hansson, JH. et al. (1995) Nature genetics 11, 76-82. PMID: 7550319 4. McDonald, FJ. et al. (1995) The American journal of physiology 268, C1157-63. PMID: 7762608 5. Goulet, CC. et al. (1998) The Journal of biological chemistry 273, 30012-7. PMID: 9792722 6. Hobbs, CA. et al. (2013) American journal of physiology. Lung cellular and molecular physiology 305, L990-L1001. PMID: 24124190 7. Saxena, A. et al. (2002) The Journal of clinical endocrinology and metabolism 87, 3344-50. PMID: 12107247 8. Strautnieks, SS. et al. (1996) Nature genetics 13, 248-50. PMID: 8640238 9. Fajac, I. et al. (2008) Respiratory research 9, 46. PMID: 18507830
Note	For research use only

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Datasheet

Human SCNN1G Recombinant Protein (N-His).pdf

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Human SCNN1G Recombinant Protein (N-His) (HD983012)

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