Human SEC61G Recombinant Protein (N-His-SUMO & C-Strep) (HD934012)

Name: Human SEC61G Recombinant Protein (N-His-SUMO & C-Strep)
Brand: abinScience
SKU: HD934012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD934012
Description	Recombinant Human SEC61G Protein, N-His-SUMO & C-Strep (HD934012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P60059
Protein length	Met1-Gly68
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Protein transport protein Sec61 subunit gamma, SEC61G
Background	Protein transport protein Sec61 subunit gamma is a ~7 kDa protein. Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER. 1. McGilvray, PT. et al. (2020) eLife 9. PMID: 32820719 2. Sundaram, A. et al. (2022) Nature 611, 167-172. PMID: 36261522
Note	For research use only

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Datasheet

Human SEC61G Recombinant Protein (N-His-SUMO & C-Strep).pdf

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Human SEC61G Recombinant Protein (N-His-SUMO & C-Strep) (HD934012)

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References

Datasheet

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