Human SIGMAR1 Recombinant Protein (N-His) (HD921012)

Name: Human SIGMAR1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD921012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD921012
Description	Recombinant Human SIGMAR1 Protein, N-His (HD921012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q99720
Protein length	Gly31-Pro223
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Aging-associated gene 8 protein, OPRS1, SIG-1R, SIGMAR1, SR-BP, SR31747-binding protein, SRBP, Sigma 1-type opioid receptor, Sigma non-opioid intracellular receptor 1, Sigma1-receptor, Sigma1R, hSigmaR1
Background	Sigma non-opioid intracellular receptor 1 is a ~25 kDa protein. Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. 1. Wang, L. et al. (2006) Experimental cell research 312, 1439-46. PMID: 16472803 2. Jbilo, O. et al. (1997) The Journal of biological chemistry 272, 27107-15. PMID: 9341151
Note	For research use only

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Datasheet

Human SIGMAR1 Recombinant Protein (N-His).pdf

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Human SIGMAR1 Recombinant Protein (N-His) (HD921012)

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