Human SLC25A11 Recombinant Protein (N-His-KSI) (HD846012)

Name: Human SLC25A11 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD846012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HD846012
Description	Recombinant Human SLC25A11 Protein, N-His-KSI (HD846012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	Q02978
Protein length	Ala140-Gly183
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Alpha-oxoglutarate carrier, Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, SLC20A4, SLC25A11, Solute carrier family 25 member 11
Background	Mitochondrial 2-oxoglutarate/malate carrier protein is a ~34 kDa protein. Catalyzes the transport of 2-oxoglutarate (alpha-oxoglutarate) across the inner mitochondrial membrane in an electroneutral exchange for malate. Can also exchange 2-oxoglutarate for other dicarboxylic acids such as malonate, succinate, maleate and oxaloacetate, although with lower affinity. Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction. Does not transport glutathione. Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, gluconeogenesis from lactate, and nitrogen metabolism. 1. Booty, LM. et al. (2015) FEBS letters 589, 621-8. PMID: 25637873 2. Cimadamore-Werthein, C. et al. (2024) The EMBO journal 43, 3450-3465. PMID: 38937634 3. Gallo, M. et al. (2011) PloS one 6, e17827. PMID: 21448454
Note	For research use only

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Datasheet

Human SLC25A11 Recombinant Protein (N-His-KSI).pdf

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Human SLC25A11 Recombinant Protein (N-His-KSI) (HD846012)

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