

| Catalog No. | HD133012 |
|---|---|
| Description |
Recombinant Human SLC5A5 Protein, N-His (HD133012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q92911 |
| Protein length | Val305-Pro340&Pro467-Ile526&Thr550-Leu643 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 22.90 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | NIS, Na(+)/I(-) cotransporter, Na(+)/I(-) symporter, Natrium iodide transporter, SLC5A5, Sodium-iodide symporter, Sodium/iodide cotransporter, Solute carrier family 5 member 5 |
| Background | Sodium/iodide cotransporter is a ~68 kDa protein. Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland. Can also mediate the transport of chlorate, thiocynate, nitrate and selenocynate. 1. Van Sande, J. et al. (2003) Endocrinology 144, 247-52. PMID: 12488351 2. Dayem, M. et al. (2008) The Journal of endocrinology 197, 95-109. PMID: 18372236 3. Wu, SL. et al. (2008) The Journal of endocrinology 199, 213-9. PMID: 18708479 4. Huc-Brandt, S. et al. (2011) Biochimica et biophysica acta 1808, 65-77. PMID: 20797386 5. Thompson, RJ. et al. (2019) Thyroid : official journal of the American Thyroid Association 29, 1485-1498. PMID: 31310151 6. Concilio, SC. et al. (2020) PloS one 15, e0229085. PMID: 32084174 7. Smanik, PA. et al. (1996) Biochemical and biophysical research communications 226, 339-45. PMID: 8806637 8. Saito, T. et al. (1997) The Journal of clinical endocrinology and metabolism 82, 3331-6. PMID: 9329364 |
| Note | For research use only |
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