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Human SLC6A3 Recombinant Protein (N-His) (HX986022)

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Overview
Catalog No.HX986022
Description
Recombinant Human SLC6A3 Protein, N-His (HX986022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% as determined by SDS-PAGE.
Expression systemE. coli
AccessionQ01959
Protein lengthSer2-Phe69
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesHomo sapiens (Human)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesDA transporter, DAT, DAT1, SLC6A3, Sodium-dependent dopamine transporter, Solute carrier family 6 member 3
Background

Sodium-dependent dopamine transporter is a ~68 kDa protein. Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling.

1. Wu, X. et al. (1999) Gene 233, 163-70. PMID: 10375632
2. Syringas, M. et al. (2000) Molecular pharmacology 58, 1404-11. PMID: 11093780
3. Giros, B. et al. (1992) Molecular pharmacology 42, 383-90. PMID: 1406597
4. Torres, GE. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 15650-5. PMID: 15505207
5. Kurian, MA. et al. (2009) The Journal of clinical investigation 119, 1595-603. PMID: 19478460
6. Li, Y. et al. (2024) Nature 632, 686-694. PMID: 39112701
7. Nielsen, JC. et al. (2024) Nature 632, 678-685. PMID: 39112703
8. Srivastava, DK. et al. (2024) Nature 632, 672-677. PMID: 39112705
9. Pristupa, ZB. et al. (1994) Molecular pharmacology 45, 125-35. PMID: 8302271
Note For research use only
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Formula
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