Human SRP54 Recombinant Protein (N-His) (HX195012)

Name: Human SRP54 Recombinant Protein (N-His)
Brand: abinScience
SKU: HX195012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HX195012
Description	Recombinant Human SRP54 Protein, N-His (HX195012) expressed in E. coli, spanning Met1-Met504. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	P61011
Protein length	Met1-Met504
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	57.87 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	EC:3.6.5.4, SRP54, Signal recognition particle 54 kDa protein, Signal recognition particle subunit SRP54
Background	Signal recognition particle subunit SRP54 is a ~55 kDa protein. Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane. Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes. Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA. 1. Lee, JH. et al. (2021) Science advances 7. PMID: 34020957 2. Carapito, R. et al. (2017) The Journal of clinical investigation 127, 4090-4103. PMID: 28972538 3. Bellanné-Chantelot, C. et al. (2018) Blood 132, 1318-1331. PMID: 29914977
Note	For research use only

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Datasheet

Human SRP54 Recombinant Protein (N-His).pdf

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Human SRP54 Recombinant Protein (N-His) (HX195012)

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