Human TBP Recombinant Protein (N-His) (HB847032)

Name: Human TBP Recombinant Protein (N-His)
Brand: abinScience
SKU: HB847032
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HB847032
Description	Recombinant Human TBP Protein, N-His (HB847032) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Expression system	E. coli
Accession	P20226
Protein length	Gly160-Thr339
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	GTF2D1, TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP, TF2D, TFIID, Transcription initiation factor TFIID TBP subunit
Background	TATA-box-binding protein is a ~37 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TBP forms the TFIID-A module together with TAF3 and TAF5. 1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473 2. Kao, CC. et al. (1990) Science (New York, N.Y.) 248, 1646-50. PMID: 2194289 3. Peterson, MG. et al. (1990) Science (New York, N.Y.) 248, 1625-30. PMID: 2363050 4. Hoffman, A. et al. (1990) Nature 346, 387-90. PMID: 2374612 5. He, Y. et al. (2016) Nature 533, 359-65. PMID: 27193682 6. Louder, RK. et al. (2016) Nature 531, 604-9. PMID: 27007846
Note	For research use only

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Datasheet

Human TBP Recombinant Protein (N-His).pdf

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Human TBP Recombinant Protein (N-His) (HB847032)

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