Human TBX2 Recombinant Protein (N-His) (HC745012)

Name: Human TBX2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC745012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HC745012
Description	Recombinant Human TBX2 Protein, N-His (HC745012) expressed in E. coli, spanning Glu102-Gly284. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q13207
Protein length	Glu102-Gly284
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	23.59 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	T-box protein 2, T-box transcription factor TBX2, TBX2
Background	T-box transcription factor TBX2 is a ~75 kDa protein. Transcription factor which acts as a transcriptional repressor. May also function as a transcriptional activator. Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes. Required for cardiac atrioventricular canal formation. May cooperate with NKX2.5 to negatively modulate expression of NPPA/ANF in the atrioventricular canal. 1. Jacobs, JJ. et al. (2000) Nature genetics 26, 291-9. PMID: 11062467 2. Sinha, S. et al. (2000) Gene 258, 15-29. PMID: 11111039 3. Lingbeek, ME. et al. (2002) The Journal of biological chemistry 277, 26120-7. PMID: 12000749 4. Wang, B. et al. (2012) PloS one 7, e41355. PMID: 22844464 5. Reinhardt, S. et al. (2019) Cellular and molecular life sciences : CMLS 76, 1005-1025. PMID: 30599067 6. Liu, N. et al. (2018) Human molecular genetics 27, 2454-2465. PMID: 29726930 7. Martin, N. et al. (2012) The EMBO journal 31, 95-109. PMID: 22002537
Note	For research use only

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Human TBX2 Recombinant Protein (N-His).pdf

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Human TBX2 Recombinant Protein (N-His) (HC745012)

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